SOCIETY MEETINGS. 
221 
normal color of the organ itself. The nodules usually appear 
freely over the surface of the spleen, are somewhat elevated in 
the centre, and measure from 1-16 to 3 - 4 inch in diameter. On 
section they appear as tough elastic or fibrous tissue containino- 
more or less of a yellowish product near their centre, which 
may be softened into purulent matter or may be charged with a 
gritty pioduct of a calcareous nature. On section of the entire 
organ we find deeply embedded in the parenchyma rounded 
well-formed nodules of a soft consistency, free in number, and 
resembling cheesy deposits. The tissue of the spleen seems 
normal m consistency, color and texture, but the oro-au itself is 
usually very much enlarged. 
The liver, somewhat enlarged by the process of chronic in¬ 
flammation during the nodular development, may be studded 
over its entire surface with small yellowish tubercles usually 
appearing in the type of miliary tuberculosis. I have noticed 
those cases where the liver was completely loaded with tubercu¬ 
lar product and not only did they appear on the surface but 
were found in large numbers in the substance of the o-land, 
often m such quantities as to destroy, by crowding, large areas 
of gland tissue and consequently greatly impair the healthy 
function of the organ. However, in well marked generalized 
cases of tuberculosis we do not always find this oro-an to be the 
seat of extensive disease. 
1 lie presence of tubercular products in the lymphatic glands 
is manifest even in the earliest stage of the disease and with 
progression the glands undergo all the changes peculiar to its 
development; often the disease is confined to the gland struc¬ 
ture alone and so long as it remains confined to such glands 
it oes little 01 no injury to the animal. In some cases, how¬ 
ever, the gland undergoes a complete change. Its parenchyma 
gnes way to the formation of a calcareous tumor. In such 
cases also little harm can arise so long as the condition remains 
local. Still, in other cases the gland undergoes a retrograde 
process and becomes broken down and necrotic, such process 
usually beginning in the centre of the gland extends toward 
the periphery. This broken down product is carried from 
the gland by the efferent vessels and poured into the blood 
stream and thus becomes the primary focus for the o-eneralized 
contamination of the system. 
Tuberculosis spreads from the primary focus in a variety of 
ways, viz; : by the lymphatic system, by the blood stream* by 
contiguity of tissue. From the primary focus we experience 
