74 
The liver exhibits slight interstitial changes; small round cells are collected 
around the portal sheaths, golden brown to blackish pigment is deposited in somt 
of the peripheral cells of the lobules and in the interspaces. The organ shows 
extensive decomposition, and large, bacilli are present. 
The kidneys evidence cloudy swelling, and the vessels are filled with blood 
The organs are too decomposed to admit of more exact determination of the change, 
present. 
The heart muscle is degenerated and the fibres show some fatty degeneration 
The muscle of the left ventricle is hypertrophied, and contains some brownish-black 
pigment granules, which do not give the iron reaction. Around the aortic r: 
is a pronounced area of old atheromatous changes, and one or two of the plaque- 
are calcified. 
The mesenteric glands show hyperplasia of the connective tissue reticulum: 
the lymphoid cells are increased, and large mononuclear and multinucleated cells 
are present. Pigment granules are found, but not in any great number. Eosino- I 
philes are especially numerous in the small retro-caecal glands. In some of the 1 
glands near the diseased bowel, spots of necrosis are found ; the lymphoid cells 
stain badly, and are very granular; polymorphonuclear leucocytes are accumulated 
in the lymph spaces. 
The Brazilian case of oesophagostomiasis corresponds to the cases 
of the disease, occurring- in apes and monkeys, described by W einberg. 
In certain important points the case in man differs. The lesions are 
more extensive in the Brazilian case ; more tumours are formed, and 
greater damage appears to have been caused to the wall of the bowel. 
The oesophagostome larvae have developed in the small intestine of 
the man, an unusual occurrence, as Weinberg has not recorded such 
a situation, and it was believed that the cysts of oesophagostomes 
were limited by the ileo-caecal valve. It is probable that the cysts 
m the ileum are of more recent development than those in the caecum 
and colon. 
em erg records the presence of an adult female cesophagostor 
and of spherical eggs measuring 52 /*, in the cyst cavity of a nodi 
taken from the caecum of a chimpanzee, and, in another case, he h 
found minute larvae in the muscular coat. In the Brazilian case 
ave no as yet succeeded in discovering either a mature worm or tl 
findm * ° re i * Um ° UrS are stl11 being sectioned in the hopes 
nreseif “/“fn which would help to explain tl 
peritoneum ^ Sma “ SeCti ° nS ° f larvae in the submucosa, - 
peritoneum and intermuscular spaces. 
ileum, eleven of'the 6 * 1 fr ° m e * amination of twe lve nodules of tl 
appendix verm f CaeCUm ' ° f the Ue °-«ecal valve, one ■ 
following conclusions being dZn^ * D ° W ° f “ 
