2 
w fth infective blood from yellow fever cases or subjected to the bites 
of infected Stegomyia calopus. The results at first were very 
erratic, but, subsequently, with improvement in technique and 
important details, the reactions were more positive and could be 
gauged with certainty. Unfortunately it has proved impossible to 
test the reactions by human inoculations, and the chimpanzees were 
too few in number to be able to prove all the different points. 
Many tests have to be made and experimental work revised at all 
points, and therefore it is considered inadvisable to make public tin- 
exact technique employed until an exhaustive report can be 
presented. The experiments were discontinued for lack of animals 
susceptible to the disease, and the expedition returned to England 
in February, 1909. A new expedition has now been organised and 
provision made for an adequate supply of chimpanzees. With 
improved accommodation for the experimental animals, and with 1 1n¬ 
experience gained from the work of the past years, it is confidently 
expected that an early and satisfactory report can be published. 
An expedition should endeavour to assist the local authorities and 
aid the medical profession. Therefore the resources of the laboratory 
in Manaos were placed at the disposal of the State, the medical frater 
nity, the hospitals, and the poor of the city. Examinations of blood, 
agglutination reactions for typhoid and paratyphoid, bacteriological 
examinations of water and milk, post-mortems and pathological 
reports were made, and the laboratory so conducted as to be of the 
greatest possible service to the community. As a consequence much 
routine work had to be performed. From the manifestations of 
sympathy and the co-operation extended to the expedition bv the 
• tate authorities and the doctors of Manaos, it is believed that the 
work of the laboratory has proved of real service. 
'ring the term of office of the 
’ and was continued under the 
de Carvalho, both of whom 
