200 
When the zygotes reach the size of 39 x 45 or 45 x 5;, 
(seven to eight and a half days) a fine reticulum could be seen 
outlining the sporoblastic chamber; while others were dotted 
throughout with coarse round granules, the sporoblasts. 
The capsule of the zygote ruptures about the eleventh day, the 
sporozoites making their way to the salivary glands, and leaving 
the collapsed, wrinkled, disc-shaped envelopes behind in the outer 
layer of the mid-gut wall. The mechanism of the passage of the 
sporozoites into the salivary glands is not known, but these glands 
are more or less filled with sporozoites after the eleventh day. 
The simple tertian zygote differs from the malignant tertian; 
first in the rapidity of its development, attaining a slightly greater 
size in a given time. In the younger zygotes the pigment is arranged 
in clumps or lines and slowly changes its position. The pigment may 
be clumped and dancing within vacuolated spaces of the zygote. In 
xpenment No. 16, tertian zygotes in Ce. albimana are 12 to 
' SM m diameter four to four and a half days after biting. The 
capsule of the zygote was well defined, but the zygote was apparently 
s !g ty argei than a malignant tertian zygote of the same age, and 
its cytoplasm was more coarsely granular than that of the malignant 
parasite. 7 he pigment is coarse and in clumps, not lines, and 
1 no motile In another specimen of Ce. albimana, in the same 
nt ' t e f >1 ^ Tnent was arranged in two lines near the periphery 
w th half me days after the first one 
refractilo ur ® ova » containe d six to eight zygotes, full of faintly 
Tviote ; equa " y . S,2ed s P° rob lasts, 3 n in diameter. These 
partly Drni^r 4 r" *” dlameter ' Four or five zygotes were seen 
54 M and ° f the ^ Tbe y were 48 b? 
and there f A > N ° P ’^ ment be detected, but here 
indicating- the'\ ° ers ln Sr° u ps, having a linear arrangement, 
evperiment th ° f Percies from sporoblasts. In this 
“Je " early reached nine days, 
only one of fi " °' 18, slmpIe tertia n sporozoites were found in 
C,^f„J e t V ;e n a a„ n da°L; f he da Sali r f ndS “ a spramenof 
acini were ; n nl ' • ‘ a ^ s a f ter the first biting. Four other 
sporozoites in AeTntoed ^ Were devoid of sporozoites - The 
duct and in several of tt j CmUS were distributed in the lumen of the 
several of the d.stended vesicular epithelial cells, seven! 
