2 3 I 
As regards increase or loss of weight in the animals under observa¬ 
tion, most of them were young, and their weights, of course, increased 
by mere growth. Heavier coats also added to the weight. Of those 
on which accurate data can be founded the results are as follow: — 
Number of animals : Rats, 19; guinea-pigs, 8. Rats: Gained weight, 
14; lost weight, 5. Guinea-pigs : Gained weight, 6 ; lost weight, 2. 
Animal 
Cold Chamber 
Coni 
rROLS 
Total 
Gained 
weight 
Lost 
weight 
Gained 
weight 
Lost 
weight 
T. letcisi (rats) . 
3 
1 
1 
1 
6 
T. equiperdum (rats) . 
6 
1 
4 
2 
'3 
T. brucei (guinea-pigs) . 
3 
- 
2 
- 
5 
Tubercle . 
- 
1 
1 
- 
2 
7 . evansi . 
- 
- 
- 
1 
1 
Total . 
12 
3 
8 
4 
27 
Put shortly, all the animals in the cold chamber gained weight 
except three, of which one was a case of tubercle: showing, on the 
whole, and as far as the small figures go, a favourable influence on 
their general nutrition. But these figures are amply supported by the 
obvious increase in weight of practically all the animals in the 
chamber, though their immaturity in most cases makes the actual 
results in grams of weight gained of less value from the point of view 
of influence of cold per se. 
Finally, as regards the temperatures of the animals, no constant 
effect could be observed in the influence of the cold chamber, and 
'hose in and those out varied equally irregularly, with no permanent 
ratio between the one and the other. 
^oteon 12 April, 1910. The result of further experiments carried 
ou t since February 21 and bringing the observation period up to over 
ei ght months is as follows 
Six guinea-pigs were inoculated with bovine tubercle (o 1 mgr. 
culture) on the 27th November, and three placed in the cold chamber 
p 
