2 6 z 
gambiense revealed by careful daily counting in a case in my * 
elsewhere) “ Stl1 ’ U " der treatment ’ wil1 ** fully reports 
M Z' u", m f e ‘ 3ged 26 ' 3 Stron ? y° un S man, torn i 
* orthumberland, was infected in North-East Rhodesia i 
ep ember, 1909, the trypanosomes being found in his blood i: 
Africa on November r 7 . On coming to Liverpool for treatment 
was admitted into the Southern Hospital on December 4. Fm 
then until February ,6 (seventy-three days) the number of 
trypanosomes in his blood was estimated only by the « 
o s in common use that is, by the proportion of trypano¬ 
somes to red cells, or leucocytes, or to ‘fields’ of the microscope 
xamined. These methods are obviously open to such great error 
1 ,.~ Can scaice, y be depended upon to indicate any but very 
1 , GrenC j S 111 dlc num bers of objects counted. During the 
' ny- iree days forty-six counts were made, but on several 
ons none was attempted for three or four days in succession; 
arrnrn/ CVCn 1 tke me thods of counting employed had been more 
tt G ’ SU Cen fluctuations might easily have been missed, 
irrpo- / ' UaS ke ex P e cted, the graph during tin’s period is very 
DatiV> f a m ° S ^ wor thless. On admission on December 4 the 
minimi aS f Cp ° rtccl to conta in about 6,000 trypanosomes per cubic 
per cuh Fe ° , ° dl and Iu ** numbers . —ting to about 3,® 
ZZy :7 7 IT:r efouad ° n December '• and2S ' 
treatment with ataxy]" W3S ^ 
doses of -> to ' nt mercury’, and received altogether ten 
never f#»li k i ^ °^ tke ^ ormer - Nevertheless, the parasites 
roughly estimated 3 ^ 2 °° ^ Cubic mi,limetre in number - 35 
Patient’s sight— f ° Unc1, however, that atoxyl was injuring the 
substituted ** \t tl SOmetl ™ es happens — and other treatment was 
Method of count 6 tl * me We e * a borated a much more correct 
(4 to 1 c.mm 'i nf 1 uT** . aI1 1,16 P arasi ’tes in measured quantities 
onward the patient^T In thlck fi,m ’ and from February 16 
method bv nn P Opanosomes were estimated daily by this 
remarkable graph obtained^ attached chart S iveS ^ 
U P to the present (April 30). 
