272 
- in the number of parasites. We should note that the comparative!} 
small numbers of P. vivax found are due to the fact that the 
specimens generally contained a large proportion of mature parasites, 
not as yet disintegrated into spores—these, of course, being absent 
from peripheral blood containing P. falciparum, in which only 
spores or young forms generally occur. There is no reason for 
considering quinine in this connection, because it probably affects 
the fever only through its action on the parasites. 
6 . The degree of fever associated with various numbers of 
parasites. We know of no extensive and exact studies on this 
point, and ours are not yet complete. On forty-seven occasions 
the number of parasites was carefully compared with the maximum 
degiee of temperature reached during the febrile paroxysm caused 
by them, and the following results were obtained: — 
P. vivax (12 occasions)— 
No. of parasites ... 
Maximum temp. °H.F. * 
No. of parasites . 
Maximum temp. H.F. 
No. of parasites . 
Maximum temp. H.F. 
Co-efficien 
P- falciparum (35 occasions)— 
No. of parasites 
Maximum temp. °H.F. 
No. of parasites 
Maximum temp. H.F. 
No. of parasites 
Maximum temp. H.F. 
No. of parasites ... 
Maximum temp. H.F. 
No. of parasites ... 
Maximum temp. H.F. 
No. of parasites ... 
Maximum temp. H.F. 
No. of parasites ... 
Maximum temp. H.F. 
Co-efficient of 
" H.F. = Haematothermic 
1,500 
1,400 
580 
440 
43 ° 
84 
IOI 
97 
102 
76 
... 260 
256 
232 
150 
•33 
76 
54 
46 
44 
3 + 
... IOO 
83 
34 
20 
correlation r 
(rigor) 
; = 0-68561 
+ 0-10318 
303,000 
58,000 
55,000 
54,00° 
5 °’ ■» 
108 
82 
88 
IOO 
9 s 
45,000 
36,000 
34,000 
31,000 
76 
26,0* 
76 
60 
86 
94 
26,000 
25,000 
16,000 
15,000 
15.°°° 
IOI 
80 
5 2 
54 
54 
15,000 
9,700 
9,000 
7 ) 5 °° 
7 r 4 CO 
70 
56 
70 
90 
4 ° 
6,700 
6,500 
83 
6,000 
5,800 
5,200 
86 
5 2 
70 
76 
4,000 
4,000 
3,600 
3,000 
2,600 
70 
40 
80 
38 
64 
2,50° 
2,000 
46 
1,860 
1,000 
zoo 
5 ° 
38 
i 5 
5 ° 
rrelation r = 
0-60331 n 
2 0-07251 
scale Fahrenheit. 
