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(5) We estimate from our cases that considerable continued 
doses of quinine reduced the asexual forms by 50 to 80 per cent. 
(6) There are strong reasons for supposing that the sexual forms 
require eight to ten days for development; that the often noticed 
long persistence of crescents is not due to their long life (as 
generally thought) but to constant replenishments of the stock by 
fresh broods; that they sometimes show a distinct tertian 
periodicity; and that quinine does not affect them when once 
generated; but ultimately reduces their numbers by destroying the 
generating cells. The sexual forms were never seen to produce 
fever. 
(7) The leucocytes are below normal during febrile periods and 
above normal afterwards. The percentage of mononuclears rises 
after paroxysms and is always in excess of the normal. 
(8) Methylene blue, soamin, X-rays, and faradic and galvanic 
currents had no results in a few experiments. 
(9) The haemoglobin falls markedly with fever, but rises rapidly 
with convalesence. 
(10) The faecal urobilin shows marked correlation with the 
occurrence of fever, and is specially studied in the accompanying 
paper by Dr. G. C. E. Simpson. 
Many other deductions may be based on our observations, but 
will be better considered after more detailed counts have been 
made. 
