3 2 6 
I. Coagulation titne of blood , by Wright's method at 37°C. ( blood 
heat). 
In order to understand the relations between the coagulation, 
leucocytes, haemoglobin and the parasites, the observations are 
tabulated below. They were made within the last fortnight of the 
patient’s illness. 
Normal (Man) 
June 14 
June 16 
June 21 
June 29 
Coagulation time ... 
3 to 6 minutes 
(4 mins. 30 secs, 
average) 
12' 0" 
5 ' * 5 " 
s’ 
Died 
Leucocytes per mm. 8 
10,000 
25,000 
4,500 
3,200 
Haemoglobin index 
(Sahli's scale) 
100% 
5 °% 
70 % 
50 % 
* Parasites per mm. 3 
38 
32 
5 6 
The observations are too few to lead to any definite conclusions, 
but one gets a general impression that the coagulation time is 
passing from the negative to the positive phase as the leucocytosis 
is passing towards leucopenia. The number of the parasites and 
the nature of the haemoglobin index are subject to very little 
variation. 
II. Absence of trypanosomes from the cerebrospinal fluid and 
blood. 
Patient died June 29th at about 5 p.m. Post-mortem made June 
30th at about 11 a.m. 
(1) The cerebrospinal fluid was carefully collected in sterilized 
tubes. It was mixed with a trace of blood and lymph (oedema of 
the brain). 
(2) Tubes were centrifugalised for fifteen minutes, the supernatant 
fluid was pipetted off, smears were made, both from the deposits and 
supernatant fluid, fixed in alcohol, stained according to the 
Romanowsky method. The result was negative. 
(3) Smears were made from the blood, fixed in alcohol stained 
with Romanowsky. Result, negative. 
* Counted by Dr. David Thomson. 
