32 7 
III. Presence of albumoses in the cerebrospinal fluid. 
(1) Acetic acid and saturated sodium chloride reactions — 
positive.* 
(2) Biuret reaction — positive. 
Besides it appeared from the methodical application of other 
tests that the albumose belonged to the class of primary proteose. 
IV. The blood was examined for the presence of albumoses. The 
result was negative. 
V. Absence of albumoses in the urine. 
The urine during life was examined for albumose. The reaction 
was negative; later on, in the preserved specimen of urine albumose 
was again found to be absent. 
Patient had a large collection of pus in the pleural cavity, 
consequently the possibility that the albumose was due to empyema 
was thus eliminated by the result of the blood and urine 
examinations. 
So that although the cerebrospinal fluid was tinged with blood, 
the process of exclusion leads to the conclusion that albumose was 
present in the cerebrospinal fluid only. According to Byrom 
Bramwellt the presence of albumins, together with lymphocytosis 
in the cerebrospinal fluid, are supposed to be of early diagnostic 
value in the incipient stage of parasyphilitic lesions like tabes and 
general paralysis of the insane. The exact origin of albumose is 
doubtful; either it may be due to chronic meningo-encephalitis or 
to toxic products of protozoa or bacteria. Whatever the cause may 
be it is evident that the presence of albumose is not restricted to 
the parasyphilitic lesions only. 
Its presence in the cerebrospinal fluid in the incipient stage of 
chronic meningo-encephalitis (T. gambiense') requires to be 
determined. But how far it may be of diagnostic value in the case 
of sleeping sickness is another question. 
VI. Presence of choline. 
Mott and Halliburton have shown that in general paralysis 
of the insane the marked degeneration that occurs in the brain is 
* Boston, Clinical Diignosis (1904), p. 216. 
t Personal communication. 
