368 
My observations as to the morphology of the parasite confirm 
those of Stephens and Fantham regarding the existence of 
posterior nuclear forms in infected rats, guinea-pigs and rabbits. I 
have also found them in monkeys (Macacus rhesus , Cercofitkecus 
callitfichus'), dogs, mice, horse and donkey. 
I have not, however, succeeded in finding these forms in the 
blood of the patient himself, in spite of very careful daily 
examinations during a period of over three months. 
Why the posterior nuclear forms should be apparently absent 
from the patient’s blood is not very obvious. Trypanosomes were 
always scanty and possibly these forms may have been missed, 
although nearly two thousand parasites were examined without 
meeting a single example of the form in question. However, the 
posterior nuclear variety is not usually seen in infected animals 
until the blood is fairly heavily infected, when they may form as 
many as five or six per cent, of the total parasites present. 
Sections of the nervous system of the patient exhibit 
well-marked perivascular infiltration and leptomeningitis. The 
spleen was greatly increased in size and deeply pigmented 
(malarial?). The cervical, axillary, mesenteric and inguinal 
lymphatic glands were considerably enlarged, and presented the 
usual histological appearances. 
