3S8 
polymorphonuclear and mononuclear ) and also large numbers of 
trypanosomes. In the deeper layers of the substantia propria there 
was marked cellular infiltration and also considerable vascular 
formation. These areas also extended in places into the anterior 
third reaching occasionally almost to the anterior homogeneous 
membrane. Trypanosomes were found scattered throughout this 
portion of the cornea and in certain spots they existed in enormous 
numbers. 
Appearances somewhat similar to the above have been described 
by Morax" as occurring in the corneae of dogs and goats infected 
with T. equiperdum. 
The state of affairs obtaining in the right cornea of Goat 3 
represented a rather more advanced stage. The substantia propria 
was about three times as thick as that of a normal cornea, and 
exhibited similar changes to those described in the previous case, 
viz., markedly oedematous areas lying side by side with patches 
of intense leucocytic infiltration. There was also some extravasation 
of red cells from the newly-formed vessels. The morbid processes 
were not, however, confined to the substantia propria, but had 
involved the anterior epithelial layer, which in places was separated 
from the substantia propria by inflammatory exudation. In these 
regions the epithelial cells were degenerated and stained badly, and 
at some points were completely disintegrated. 
In contradistinction to the previous case only few trypanosomes 
were iound scattered throughout the substantia propria. 
II. 1 hose which were slightly opaque at the time of death, viz., 
1 ight cornea ol Goat 1 and of Goat 2 and the left of the horse. Here 
the lesions were limited to the substantia propria which was slightly 
mu eased in thickness. In the deeper layers near the corneo- 
sclerotic junction there was considerable cellular infiltration and 
slight vascular formation. Elsewhere the only change visible was 
a slightly oedematous condition with the occurrence of a few 
leucocytes and trypanosomes scattered throughout the interlamellar 
spaces. 
III. I he left cornea of Goat 2, which after being densely 
o paque had subsequent ly become perfectly clear again. The 
Pasteur^roo^n 31 '^ 115 ocu,aires au cours des Trypanosomiases,’ Annales de ITnstitui 
