III. CORRELATION BETWEEN THE CYCLE AND THE 
AMOUNT OF FEVER 
From the chart one can observe that almost invariably the 
temperature tends to be higher during the height of the cycle, and 
that between the rises the temperature keeps lower. 
In the table average daily temperatures are recorded. These 
figures were obtained by taking the average of the four-hourly 
temperatures observed during the twenty-four hours of each day. 
We think that this figure gives a fair representation of the amount 
of fever for the day, and in this table it may be noted that the 
average daily temperature rises coincidentlv with the increase of 
trypanosomes and falls with their fall. 
IV. OTHER CLINICAL OBSERVATIONS AND CORRELATIONS 
WITH THE CYCLE 
lhe pulse rate ranged all through this case from go to 120 per 
minute. During the height of the cycle it tended to increase 
coincident ly with the increased amount of fever. The respiration 
rate ranged from 20 to 28 per minute, tending also to increase with 
the rise of the trypanosomes. 
With regard to the bowels there is little to note. Their action 
uas ea sily regulated with small doses of cascara. It was very 
noticeable that the patient was more drowsy, and tended to have 
headaches, during the commencement of the cyclical rise, but these 
symptoms abated at the extreme height and during the subsequent 
fall of trypanosomes. 
lhe lymphatic glands in the neck, axilla, groin, and popliteal 
space were more or less always swollen, but this condition was 
greatly aggravated at intervals, accompanied with marked 
tenderness, though only sometimes was this coincident with a 
trypanosome increase. 
I lie urine throughout remained clear, usually slightly acid ana 
without deposits. The specific gravity ranged from 1010 to 1026. 
On March 15 he had a diffuse ill-defined erythematous rash over 
his left leg, occurring just before the height of a trypanosome 
increase. 
