465 
THE LIFE-HISTORY OF TRYPANOSOMA 
GAMBIENSE AND TRYPANOSOMA 
RHODESIENSE AS SEEN IN RATS AND 
GUINEA-PIGS* 
BY 
H. B. FANTHAM, D.Sc. Lond., B.A. Cantab., A.R.C.S. 
(. Received for publication 15 October , 1910) 
Plate XXVII. 
CONTENTS PA<it 
Introduction .. . ••• . 
Methods ... ... ... ... ... ••• ••• ••• •” 
Resume of previous work on Latent Bodies of Trypanosomes . ••• A, 
The Relation between Latent Bodies and the number of Trypanosomes in the 
Peripheral Blood, with Notes on the Parasites found in the Internal Organs ot ^ 
the Hosts . . 
The Formation of Latent Bodies from Flagellate Trypanosomes ■ 
The Structure of Latent Bodies .- 
The Metamorphosis of Latent Bodies into Trypanosomes ... 
The Significance of the Non-Hagellate or Latent Forms of Trypanosomes, 
tion with Latent Bodies produces Trypanosomiasis 
Note on the Degeneration of Trypanosomes ... . 
Summary and Conclusions ... . 
References. . 
Explanation of Plate . 
INTRODUCTION 
The researches recorded in this paper were undertaken at the 
suggestion of Major Ross, who wished me to investigate tie 
parasitological aspect of the numerical cyclical developmen 
discovered by him and Dr. D. 1 homson (19 10 ) * n ^ ie trypanoso 
occurring in a patient suffering from sleeping sickness contrac e 
in Rhodesia, particularly as regards the possible connection o e 
latent bodies of Salvin-Moore and Breinl (i 9 ° 7 ) * a ^ . 
lhe investigations have been conducted in the Liverpoo c 
l'ropical Medicine, under a grant from the Tiopica 
Research Fund. __ __ 
•Read before the Royal Society on December S. i 9 IO > and re P r,ntcd from ° 
HAol. LXXXIII, pp. 212-227. 
nocula 
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