487 
EXPERIMENTS ON THE TREATMENT 
OF ANIMALS INFECTED WITH 
TRYPANOSOMES BY MEANS OF 
ATOXYL, VACCINES, COLD, X-RAYS 
AND LEUCOCYTIC EXTRACT; ENU- 
MERATIVE METHODS EMPLOYED* 
BY 
Prof. Major R. ROSS, C.B., F.R.S., 
AND 
J. G. THOMSON, M.A., M.B., Ch.B. 
{Received for publication 15 October , 1910) 
Ihese experiments were conducted with funds given by Sir 
bdwin Durning-Lawrence, Bart., for the purpose of testing the 
died of cold on disease, and were suggested by one of us (R.R.) as 
a part of the studies made in connection with his case of sleeping 
sickness, as reported upon in an accompanying paper by him and 
Dr. David 1 homson. Although many researches have been made on 
'He eflect of atoxyl and other drugs, we believe that these are the 
liist in which that effect has been measured by regular daily counts 
the parasites by measured thick-film methods. 
M , I. ATOXYL 
'■ <l j 'Small doses. 
From a study of the patient, W.A., at the Royal Southern 
Hospital by Major R. Ross and D. Thomson it will be noted that 
atoxyl failed to be of any marked benefit to the patient, and in 
’he doses administered there was no trypanocidal action detected. 
H was necessary, therefore, to begin a series of experiments on 
animals inoculated with T. rhodesiense (Stephens and Fantham !), 
nilk| .*, A " attract of this paper was read before the Royal Society on December 8th, 1910, and 
P li.hcd m Proc. Roy. Soc., B, Vol. LXXXIII, pp. 227-234 (19* 0 * 
p t Pr °f- Roy- Soc., Series B, Vol. LXXXIII, pp. 28-33 (1910), and Ann. Trop. Med. and 
,,VoL IV, pp . 343.35,. 
