auto-agglutination of red 
BLOOD CELLS IN TRYPANOSOMIASIS* 
BY 
WARRINGTON YORKE, M.D. 
Received for publication 2 November, 1910) 
{F , 0 „, the Runcorn Research Laboratories of the Liverpool School of 
Tropical Medicine .) 
contents 
PAGE 
529 
53 ' 
532 
Introduction ••• ••• ••• 
Effect of Temperature on the Reaction between Agglutinin and Red B ood Ce s 
Ab.orp.ion of Ao.o-.gglo.inio Iron. Scorn b, .he Red Blood Cell, of the - 
Animal . 
Reversibility of the Reaction between Auto-agglutinin and Erythrocytes ... 
Auto-agglutinin present in the Plasma of many Normal Annuals ... ” " 
ReU.io„ .1 Ao.o-.gglo.inin of Nom»l Blood .o flu. preen. » .he Blood of 
Infected Animals . 
Effect of Heat on Auto-agglutinin . "* R . . r- e n s ; n 
Significance of the Phenomenon of Auto-agglutmat.on of Re Auto- 
Top.no.o m .l Infection.. C.c.c of J.oJTpre.ent in 
agglutinin in these Diseases. Iso . \nto- Iso-, and Hetero¬ 
excess in the Blood of Infected Animals. Are Auto , , 
agglutinin Distinct Specific Bodies f . 
Value of the Phenomenon as a Diagnostic Sign . 
INTRODUCTION 
l t is now a well-recognised fact that the erythrocytes into* 
preparations of the blood of sleeping sickness i cases ^ ^ ^ 
infected with trypanosomiasis frequent y ex n 
marked degree of agglutination. Attention *»*£*££ 
phenomenon in ^ by Kanthack Dmham and^Bland^ ^ 
found that the red blood cells o ____ 
•Reprinted from P'oc. Roy. Soc., B. Vol. LXX * IIX ^ P * Vq , LXIV) p. 100. 
t' On Nagana or Tsetse Fly Disease, Roy. Soc. P 9 
534 
537 
538 
539 
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