CONTENTS. 
XXV 
2. Substances which behave like the Digitalins. 
SECTION PAGES 
576. Apocynin and other Glucosides ........ 458 
III. SAPONIN — SAPONIN SUBSTANCES 
577. List of certain Saponins ......... 459 
578. Properties of Saponin—Sapogenin—Saporubrin ..... 459, 460 
579. Effects of Saponin on Animal Life ....... 461 
580. Action on Man ........... 461 
581. Separation of Saponin . . . . . . . . .461, 462 
582. Identification of Saponin ......... 462 
Division III. —Various Vegetable Poisonous Principles not readily 
ADMITTING OF CLASSIFICATION IN THE PREVIOUS DIVISION. 
I. SANTONIN. 
583. Properties of Santonin—Tests . 
584. Poisoning by Santonin .... 
585. Fatal Dose ....... 
586. Effects on Animals ..... 
587. Effects on Man ...... 
588. Post-mortem Appearances .... 
589. Separation of Santonin from the Contents of the 
II. MEZEREON. 
590. The Daphne mezereum —Mezereic Acid 
III. ERGOT OF RYE. 
591. Description of the Ergotised Grain ....... 
592. Chemical Constituents of Ergot ........ 
593. Ergotinine, Extraction of ........ 
594. Ergotinine—Formula and Properties ....... 
595. Ergotoxine ............ 
596. Hydroxy-phenyl-ethyl-amine (Tyramine) ...... 
597. 4-/?-Amino-ethyl-glyoxaline (Ergamine)—Amino-butylene-guanidine 
(Agmatine)—Acetyl-chlorine ........ 467, 468 
598. Ergothioneine—Fixed Oil of Ergot—Trimethylamine . . . 469 
599. Detection of Ergot in Animal Matters ...... 469,470 
600. Pharmaceutical and other Preparations . . . . . . 470,471 
601. Ergotism—Epidemics recorded in the Sixteenth, Seventeenth, 
Eighteenth, and Nineteenth Centuries ...... 471 
602. The Convulsive Form of Ergotism ....... 471 
603. The Gangrenous Form of Ergotism—The Wattisham Cases . . 472, 473 
604. Symptoms of Acute Poisoning by Ergot ...... 473 
605. Physiological Action as shown by Experiments on Animals—Sphacelic 
Acid—Cornutin .......... 473-475 
465 
466 
466 
466 
467 
467 
467 
Stomach 
462, 463 
463 
463 
463 
463, 464 
464 
464, 465 
IV. PICROTOXIN, THE ACTIVE PRINCIPLE OF THE COCCULUS INDICUS. 
606. Definite Crystalline Principles in the Berries ..... 475 
607. Picrotoxin—Properties and Reactions—Picrotin .... 475-477 
608. Tests for Picrotoxin .......... 477 
609. Fatal Dose ............ 477-478 
610. Effects on Animals .......... 478 
611. Effects on Man. 478, 479 
612. Physiological Action .......... 479 
613. Separation from Organic Matters ....... 479 
