X 
POISONS : THEIR EFFECTS AND DETECTION. 
III. STATISTICS. 
SECTION PAGES 
20. General Discussion on the Statistics of Poisoning .... 26 
21. Deaths from Poison during Five Years ending 1916, with Table . 26-28 
22. Order of Fatality .......... 28, 29 
IV. THE CONNECTION BETWEEN TOXIC ACTION AND CHEMICAL COMPOSITION. 
23. The Influence of Hydroxyl—The Replacement of Hydrogen by a 
Halogen—Bamberger’s Acylic and Aromatic Bases . . . 29, 30 
24. The Replacement of Hydrogen by Alkyls in Aromatic Bodies— 
Hinsberg and Treupel’s Observations—Overton’s Studies on the 
Solubility of Narcotics in Oil—Meyer’s Deductions from a Study of 
the “ Partition Coefficient ”—Estimation of the “ Partition 
Coefficient ^ . 30-35 
25. The Influence of Carbonyl Groups.35, 36 
26. Oscar Loew’s Theory as to Action of Poisons ..... 36-38 
27. Physiological Action of the Tropeines ...... 38-40 
28. The Anaesthetic Properties of Amino-alkyl Esters .... 40 
29. Adrenaline—Barger and Dale’s Investigations on the Physiological 
Action of Amines of Similar Structure to Adrenaline . . . 40, 41 
30. Protozoacidal Drugs .......... 41, 42 
31. Stereochemical Influences ......... 42 
32. Michet’s Experiments on the Relative Toxicity of Metals . . . 42, 43 
V. LIFE-TESTS : THE ACTION OF POISONS ON THE LOWER FORMS OF LIFE. 
33. Action on the Red Blood Corpuscles—on Infusoria—on Cephalopoda 
—on Insects ........... 43-45 
34. Effect of Poisons on the Heart of Cold-blooded Animals . . . 45-48 
35. Effect of Poisons on the Iris ........ 48 
VI. GENERAL METHOD OF PROCEDURE IN SEARCHING FOR POISON. 
36. Concentration in a Vacuum—Drying the Substance—Solvents . . 49-52 
Methods of destroying Organic Matter when searching for Mineral Poisons 
(especially Arsenic). 
37. Destruction by Heat — Basic Method — J. Ogier’s Method — A. 
Villier’s Method—Process of Armand Gautier—Duret’s Method— 
Pagel’s Process ..52-56 
VII. MICROSCOPIC INVESTIGATION OF CRYSTALS. 
38. The Petrological Microscope—Angles—Ascertaining the Refractive 
Index—Method of Due cle Chaulnes—Positive and Negative 
Refraction.56-62 
VIII. THE SPECTROSCOPE AS AN AID TO THE IDENTIFICATION OF POISONS. 
39. The Micro-Spectroscope—Curves of Position of Absorption Bands 62-65 
Examination of Blood or of Blood-Stains. 
40. General Appearance of Blood-Stains—Dragendorff’s Method of 
Solution.65, 66 
41. Spectroscopic Appearances of Blood—Spectrum of Hydric-sulphide 
Blood—of Carbon-oxide Haemoglobin—Methaemoglobin—of Acid 
Hacmatin—Tests for CO Blood—Piotrowski’s Experiments on CO 
Blood—Preparation of Hsematin Crystals—The Guaiacum Test for 
Blood.66-71 
42. Distinction between Animal and Human Blood—Biological Method 
for Human Blood.71-73 
