MORPHINE. 
297 
§ 36l.] 
Morphine Acetate. 
11*70 parts of water by weight at 15° dissolve 1 part of morphine 
acetate. 
61- 50 parts of water by weight at 100° dissolve 1 part of morphine 
acetate. 
68-30 parts of alcohol by weight (-820 specific gravity) at 15° dissolve 
1 part of morphine acetate. 
13-30 parts of alcohol by weight (-820 specific gravity) at 100° dissolve 
1 part of morphine acetate. 
Morphine Hydrochloride. 
23-40 parts of water dissolve at 15° 1 morphine hydrochloride. 
•51 part of water dissolves at 100° 1 morphine hydrochloride. 
62- 70 parts of alcohol (-820 specific gravity) dissolve at 15° 1 morphine 
hydrochloride. 
30-80 parts of alcohol (-820 specific gravity) dissolve at 100° 1 morphine 
hydrochloride. 
Morphine Sulphate. 
21-60 parts of water at 15° dissolve 1 morphine sulphate. 
•75 part of water at 100° dissolves 1 morphine sulphate. 
701-50 parts of alcohol (-820) at 15° dissolve 1 morphine sulphate. 
144-00 parts of alcohol (-820) at 100° dissolve 1 morphine sulphate. 
§ 361. Constitution of Morphine and Codeine. —Morphine is a 
tertiary base. It forms diacetyl and dibenzoyl derivatives; hence it 
contains two hydroxyl derivatives, one a phenol, the other an alcohol. 
Morphine when mildly oxidised forms pseudomorphine identical with 
natural pseudomorphine. 
2C 17 H 19 N0 3 +0 -* (C 17 H 18 N0 3 ) 2 +H 2 0 
Pseudomorphine. 
Sulphuric, hydrochloric, phosphoric, and oxalic acids, the alkalies, 
and zinc chloride have a twofold action on morphine, giving conden¬ 
sation products and a dehydration product, apomorphine C 17 H 17 N0 2 , 
which has a powerful emetic action. Apomorphine is an amorphous base 
soluble in alcohol, ether, and chloroform. Codeine is the monomethyl 
ester of morphine, 
Ci 7 H 17 NO(OH)(OH) C 17 H 17 NO(OH)(OCH 3 ) 
Morphine. Codeine. 
Codeine by loss of water yields apocodeine C 18 H 19 N0 2 . By treating 
codeine with concentrated hydrochloric acid at 100°, chlorcodide, 
Ci 8 H 20 C1NO 2 , is obtained ; on heating this with hydrochloric acid at 
150°, methyl chloride and apomorphine result. Morphine has been 
