DIAMINES. 
525 
§ 69O.] 
Neuridine platinochloride, C 5 H 14 N 2 2HCl.PtCl 4 , yields 38-1 per cent, 
of platinum ; it crystallises in flat needles, soluble in water, from which 
it is precipitated on the addition of alcohol. 
The aurochloride has the formula C 5 H 14 N 2 2HC12AuC1 3 ; it is rather 
insoluble in cold water, and crystallises in bunches of yellow needles. 
On ignition, it should yield 50-3 per cent, of gold. 
The picrate, C 5 H 14 N 2 ,2C 6 H 2 (N0 2 ) 3 0H, is almost insoluble in cold 
water, and crystallises in needles. It is not fusible, but decomposes 
at about 230°. 
Neuridine is not poisonous. 
§ 690. Cadaverine (Pentamethylenediamine, C 5 H 14 N 2 = NH 2 CH 2 — 
CH 2 —CH 2 —CH 2 CH 2 NH 2 ) is formed in putrid animal matters, and in 
cultures of the genus Spirillum. It has been found in the urine and 
fseces in cases of cystinuria, and Roos 1 has separated it by the benzoyl- 
chloride method from the fseces of a patient suffering from tertian ague. 
It may be formed synthetically by dissolving trimethylcyanide in 
absolute alcohol, and then reducing by sodium (Mendius’ reaction). 
Cadaverine is a thick, clear, syrupy liquid, with a peculiar coniine- as 
well as a semen-like odour. It absorbs eagerly C0 2 from the air, and 
ultimately is converted into a solid crystalline mass. It volatilises with 
the steam when boiled with water, and may be distilled in the presence 
even of the caustic alkalies and the alkaline earths without decomposition. 
It does not give oil of mustard when treated with CS 2 and mercuric 
chloride, nor does it give with chloroform and alcoholic potash, carbyl- 
amine (isonitrile). If dehydrated by KHO, it boils at from 115°-120° 
( Brieger). 2 
When cadaverine is treated with methyl iodide, two atoms of hydrogen 
may be replaced with methyl, forming the base C 5 H 12 (CH 3 ) 2 N 2 ; the 
platinochloride of this last base crystallises in long red needles. 
Cadaverine forms well-defined crystalline salts as well as compounds 
with metals. 
Cadaverine hydrochloride, C 5 H 14 N 2 2HC1, crystallises in needles which 
are deliquescent, or it may be obtained from an alcoholic solution in 
plates. The crystals are insoluble in absolute alcohol, but readily 
soluble in 96 per cent, alcohol. Putrescine hydrochloride, on the other 
hand, is with difficulty soluble in alcohol of that strength ; hence the 
two hydrochlorides can be separated by taking advantage of their differ¬ 
ence in solubility in 96 per cent, alcohol ; but the better method for 
separation is the benzoyl-chloride process (p. 517). On dry distillation 
cadaverine hydrochloride decomposes into NH 3 ,HC1 and piperidine 
C 5 H 11 N. The compound with mercury chloride—C 5 H 14 N 2 2HCl,4HgCl 2 
(Hg = 63*54 per cent.), melting-point 214°-216°—is insoluble in alcohol 
1 Zeit. f. physiol. Chem., xvi., 1892. 
2 Brieger has also given to the pure base a boiling-point of 175°. 
