1042 Wisconsin Academy of Sciences , Arts, and Letters. 
1890 
Oleoresina Cubebae 
Oleoresin of Cubeb 
Cubeb, 1 in No. 30 powder,’ five hun¬ 
dred grammes .500 Gm. 
Ether, 3 a sufficient quantity. 
Put the Cubeb into a cylindrical 
glass percolator, provided with a 
stop-cock, and arranged with a cover 
and receptacle suitable for volatile 
liquids. 4 Press the drug firmly, and 
percolate slowly with ether, added in 
successive portions, until the drug is 
exhausted. 5 Recover the greater part 
of the ether from the percolate by 
distillation on a water-bath, 6 and, hav¬ 
ing transferred the residue to a cap¬ 
sule, allow the remaining ether to 
evaporate spontaneously. 7 
Keep the product in a well-stop¬ 
pered bottle. 9 
NOTE. Oleoresin of Cubeb de¬ 
posits, after standing for some time, 
a waxy and crystalline matter, which 
should be rejected, only the liquid 
portion being used. 8 
Preparation: Trochisci Cubebae. 
1900 
Oleoresina Cubebae 
Oleoresin 
Cubeb, 1 in No. 30 powder, 2 five hun¬ 
dred grammes .500 Gm. 
Alcohol, 3 a sufficient quantity. 
Introduce the cubeb into a cylindri¬ 
cal glass percolator, 4 pack the powder 
firmly, and percolate slowly with al¬ 
cohol, added in successive portions, 
until the cubeb is exhausted. 6 Re¬ 
cover the greater part of the alcohol 
from the percolate by distillation on 
a water-bath, 6 and, having transferred 
the residue to a dish, allow the re- 
of Cubeb 
maining alcohol to evaporate, with 
constant stirring, in a warm place. 7 
Keep the oleoresin in a well-stoppered 
bottle. 9 
NOTE. Oleoresin of cubeb de¬ 
posits, after standing for some time, 
a waxy and crystalline matter, which 
should be rejected, the liquid portion 
only being used. 8 
Average dose. — 0.500 Gm. = 500 
milligrammes (7% grains.) 
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