1046 Wisconsin Academy of Sciences, Arts, and Letters. 
factors influencing the yield appear to be the variation in the 
volatile oil content of the drug from which the oleoresin is pre¬ 
pared and the conditions under which the preparation of the 
latter has been accomplished. As the volatile oil content of 
the cubeb fruit is stated to vary from 10 to 18 per cent., a var¬ 
iation of even greater magnitude is to be expected in the amount 
of oleoresin obtained. While this (is true when a vacuum pan is 
employed in the evaporation of the solvent, the difference is 
not so great when the pharmacopceial directions are followed 
as the loss in volatile oil in this case is relatively greater when 
the fruits contain a large amount of this constituent than when 
only a small amount is present. The difference is still further 
decreased when the solvent is evaporated on a water bath under 
ordinary atmospheric pressures. The following tables show 
the yield of oleoresin obtained with the use of various solvents: 
