UlitkMNM! 
Du Mez—The Galenical Oleoresins. 
1057 
Ash content: The ash content of the oleoresin varies with 
the solvent employed in its preparation as is shown in the first 
of the tables which follow. The highest values were obtained 
for the official product, in the preparation of which alcohol 
was the solvent used. The camparatively low ash content ob¬ 
tained for the commercial samples examined, while suggesting 
the use of some other solvent in the manufacture of these 
preparations, is thought to have been due to the greater amount 
of volatile matter (essential oil) present. Although copper 
was detected in the ash of all of the commercial products, the 
quantities present were too small to effect the value of this 
constant to any considerable extent. The following tables 
give the ash content of the oleoresin as reported in the litera¬ 
ture and as determined in the laboratory: 
Table 55. — Ash contents of oleoresins prepared in the laboratory. 
Sample 
No. 
Date 
Observer 
Solvent 
Per cent of 
ash 
1 . 
1.916 
DuMez . 
Alcohol. 
0.45 
2......... 
Acetone.... 
0.20 
3 . 
“ 
Ether. 
0.13 
4. 
Petrol t ether.. 
0.07 
5 . 
“ 
Alcohol .. 
0.48 
6. 
6. 
Acetone .... 
0.22 
7......... 
“ 
Ether ... 
0.15 
8 . 
Alcohol . 
0.51 
Table 56 — Ash contents of commercial oleoresins. 
Date 
Observer 
Source 
Per cent, 
of ash 
1893 
Dieterich ... 
Germany. 
0.50 
1894 
0.52 
1895 
“ .... 
“ 
0.47 
1897 
44 
44 
0.10 
1905 
; 
44 
0.87 
1916 
DuMez. 
Squibb & Sons.... 
0.21 (») 
Sharpe & Dohme. 
0.40 
“ 
Parke, Davis & Co___ 
0.35 
64 
Lilly & Co...... 
0.29 (!) 
Stearns & Co. 
0.37 
Sample 
No. 
1 
1 
1 
1 
Foreign con¬ 
stituents 
Copper 
1 Unevaporated solvent (alcohol) probably present. 
Acid number: The acid numbers of the oleoresins prepared 
in the laboratory varied from 21.8 to 26.7, depending on the 
nature of the solvent employed in their preparation. The num- 
67—S. A. L. 
