1060 Wisconsin Academy of Sciences, Arts, and Letters. 
Table 61 — Iodine values of oleoresins prepared in the laboratory. 
Sample 
No. 
Date 
Observer 
Solvent 
Iodine 
value 
1. ....... 
1916 
DuMez,.................. . 
A Icobol........_ ......... 
126.0 
2 ......... 
Acetone ............. .... 
131.6 
3... 
“ 
Ether ..... 
138.5 
4......... 
“ 
Petrol, ether ... .. 
141.8 
1 ........ 
45 
Alcohol ..... 
130.0 
2 ......... 
44 
Acetone. . 
113.2 
3 .. 
44 
Ether .................. ... 
115.6 
1 . 
4 . 
Alcohol .................... 
92.0 
1 
Table 62 — Iodine values of commercial oleoresins. 
Sample 
No. 
Date 
Observer 
Source 
Iodine value 
1 ......... 
1916 
DuMez. . ........ 
Squibb & Sons............. 
130.6 1 
2 ......... 
Lilly & Co.................. 
136.7 1 
3......... 
44 
44 
Parke, Davis & Co... .... 
146.9 
4..... ... 
45 
Sharp & Dohme........... 
147.3 
5 __ 
44 
44 
Stearns & Co. ............. 
147.6 
1 Unevaporated solvent probably present. 
Other Properties. 
The oleoresin, upon long standing, forms a white deposit 
consisting of cubebin, indifferent resin, cubebic acid and thick¬ 
ened oil. As the greater part (80 per cent.) 1 of this precipitated 
material consists of the therapeutically inert cubebin, 2 the 
United States Pharmacopoeia -directs that it be removed before 
dispensing the preparation. 
Special Qualitative Tests. 
The methods which have been devised for the indentification 
of this oleoresin or as a test for its quality are based on the 
fact that characteristic color changes are produced when it is 
acted upon by certain acids. Sulphuric, sulphomolybdic 3 and 
1 Schmidt (1870). 
3 See under "Constituents of therapeutic importance". 
* Dieterich, in 1897, pointed out that sulphomolybdic acid might be used 
in place of sulphuric acid. The resulting color, however, was stated to be 
a cherry-red instead of a blood-red. 
