1078 Wisconsin Academy of Sciences, Arts, and Letters. 
As will be noticed this difference in solubility is quite pro¬ 
nounced and it should, therefore, serve as a ready means of 
identifying the solvent used in the manufacture of the prepara¬ 
tion. 
Specific gravity: At 25°C a specific gravity of 1.020 to 1.086 
was found for this oleoresin when acetone or ether were em¬ 
ployed in its preparation. This constant was observed to be 
slightly higher when alcohol was used as a menstruum and con¬ 
siderably lower (less than 1.000) when petroleum ether was em¬ 
ployed. In the case of the commercial samples examined, a low 
specific gravity is to be attributed to the presence of unevapor¬ 
ated solvent in one instance, and in the other, it is thought to be 
due to an abnormally large volatile oil content. The data ob¬ 
tained in the examination of laboratory and commercial samples 
are given in the tables which follow. 
Table 66 — Specific gravities of oleoresins prepared in the laboratory, 
Sample 
No. 
Date 
Observer 
Solvent 
Specific 
gravity^ 
L. 
1916 
DuMez... 
Alcohol. 
At 25° C 
1.041 
1.030 
1,033 
1.036 
1.020 
0.990 
2.. ...... 
Acetone. 
3. ...... 
4.... 
“ 
“ 
5. .. 
Ether... 
6. ....... 
* 
Petrol, ether...._....... 
Table 67 —Specific gravities of commercial oleoresins. 
Sample 
No. 
Date 
Observer 
Source 
Specific 
gravity 
1. 
1916 
DnMez. . 
Squibb & Sons.. 
At 25° C 
0.997 1 
1.014 
1.024 
2. 
Sharp & Dohme.. 
3.. 
«4 
Lilly & Co....... 
1 Contained ether. 
Refractive index: A refractive index of about 1.517 at 25°C 
was observed for the preparations made in the laboratory with 
acetone or ether. When alcohol was employed in extracting the 
drug, the resulting product was found to have a slightly higher 
refractive index, while petroleum ether yielded an oleoresin in 
