Du Mez—The Galenical Oleoresins. 
1087 
easily perceptible in dilutions of 1 to 30,000. In view of the 
fact that personal idiosyncrasy must be a factor in applying this 
test, the use of the previously described method for the estima¬ 
tion of the gingerol content is thought to be more preferable for 
use in this connection. 
Adulterations 
There is no evidence to show that the oleoresin as prepared 
for pharmaceutical use is adulterated. La Wall, 1 however, states 
that the commercial article used in the manufacture of 
ginger ale frequently contains oleoresin of capsicum. 
A trace of copper was found in most of the commercial 
samples examined. See under “Ash content.’’ 
OLEORESIN OF LUPULIN 
Synonyms 
Aetlnerisches Lupulinextrdkt, Nat. Disp. 1879. 
Extractum Lupulini, Hirsh, Univ. P. 1902, No. 1222. 
Extractum Lupulini aethereum, Nat. Disp. 1879. 
Oleoresina Lupulinae, U. S. P. 1860. 
Oleoresina Lupulini, U. S. P. 1880. 
Oleortisine de Lupuline, U. S. Disp. 3 907. 
Ethereal Extract of Lupulin, King’s Am. Disp. (1900), p. 1333. 
History 
The first mention of the oleoresin of lupulin which could be 
found in pharmaceutical literature appeared in Procter’s article, 
“Formulae for fluid extracts in reference to their more general 
adoption in the next Pharmacopoeia, ’ 9 published in 1859. 
Procter’s oleoresin was in reality an ethereal extract, ether hav¬ 
ing been the menstruum employed in exhausting the drug. In 
this connection, it is interesting to note that the extract prepared 
with the use of alcohol had previously been brought to the 
notice of the American pharmacist by Livermore in 1853, while 
the attention of the European pharmacist had been directed to 
the same by Planche as early as 1823. The oleoresin was first 
admitted to the United States Pharmacopoeia in 1860, in which 
it remained official for more than half a century, having been 
1 La Wall (1910). 
