1092 Wisconsin Academy of Sciences, Arts, and Letters , 
Yield 
The yield of oleoresin to ether is usually given in the text¬ 
books and treatises on pharmacy as 50 to 60 per cent., while a 
yield of 32.49 to 70.8 per cent, has been reported in the journals. 
The irregularity in the quality of the lupulin as ordinarily found 
on the market very likely accounts for this variation. The 
drug, when of good quality should give a yield of at least 60 
per cent. The following tables show the variation in the yield 
as reported in the literature, also, the results obtained in the 
laboratory. 
Table 91 —Yield of oleoresin as reported in the literature. 
Date 
1853 
1888 
189 :' 
1892 
1907 
1903 
1909 
1909 
1909 
1911 
1911 
1913 
1913 
1913 
1914 
1915 
Observer 
Yield of oleoresin to— 
Alco¬ 
hol 
Ace¬ 
tone 
Ether 
Other 
solvents 
Livermore. 
Per ct. 
66.00 
Per ct. 
Per ct. 
Per ct. 
Trimble. 
60.59 
70.80 
66.50 
52.00 
65.00 
56.00 
54.00 
60.10 
66.70 
34.00 to 
65.80 
47.00 
50.00 
53.00 
57.70 
58.90 
62.10 
60.0+ 
44.94 to 
65.60 
63.96 to 
77.82 
Below 
60.00 
32.49 
55.18 
57.06 
44.20 
54.70 
55.00 
55.30 
55.50 
57.10 
58.60 
68.20 
69.20 
j Benzin 
( 7.04 
Reringer. 
71.00 
Sherrard. 
Van der Harst 
Dohme and En- 
gelhardt. 
Parson,.. 
Rernegan. 
Dohme & En¬ 
gel hardt . 
Rernegan. 
Francis. 
ftane. 
Patch. 
Engelhardt. 
Rippetoe. 
fi-lickman. 
Remarks 
Results obtained In the ex¬ 
traction of 10 samples of lu¬ 
pulin. 
Seven of 8 samples yielded 
more than 60 per cent, of ex¬ 
tractive to ether. 
Results obtained in the ex¬ 
traction of 4 samples of lu¬ 
pulin. 
Results obtained in the ex¬ 
traction of 53 samples of lu¬ 
pulin. 
Eight of 12 samples of lupulin 
extracted gave below 60 per 
cent, of ether soluble matter. 
