Du Mez—The Galenical Oleoresins. 
1113 
Chemical Properties. 
Loss in weight on heating: The oleoresins prepared in the 
laboratory, using ether and acetone as menstrua for exhausting 
the drug, lost 7.87 and 7.92 per cent, of their weight, respec¬ 
tively, on heating at 110°C. In the case of the only com¬ 
mercial sample examined, the loss was about one-half as 
great due very likely to a smaller amount of volatile matter 
(essential oil) being contained in the drug from which the lat¬ 
ter was prepared. The results obtained are given in the 
tables which, follow. 
Table 113 —Laboratory preparations—loss in weight on heating. 
Sample 
No. 
Date 
Observer 
Solvent 
Per cent, of 
loss on 
heating 
1. 
1916 
DuMez. 
Acetone. 
At 100° C 
7.92 
7.87 
2. 
Ether. 
Table 114 —Commercial oleoresins—loss in weight on heating. 
Sample 
No. 
Date 
Observer 
Source 
Per cent, of 
loss on 
heating 
1 ....._ 
1916 
DuMez... 
Sharp & Dohme. 
At 110° C 
3.35 
Ash content: The results obtained in the determination of 
the ash content of the oleoresins examined in the laboratory are 
given in the tables which follow. Aside from the fact that the 
amount of ash obtained varied with the solvent used in the 
making of the preparations, the only items of importance 
brought out by these results are that ether was evidently em¬ 
ployed in the manufacture of the commercial product and that 
the latter contained copper. 
Table 115 —Ash contents of oleoresins prepared in the laboratory. 
Sample 
No. 
Date 
Observer 
Solvent 
Per cent, 
of ash 
1. 
1916 
DuMez... 
Acetone. 
0.18 
2. 
Ether . 
0.09 
