1116 Wisconsin Academy of Sciences , Arts, and Letters. 
Table 121 —Iodine values of oleoresins prepared in the laboratory. 
Sample 
Wo. 
Date 
Observer 
Solvent 
Iodine value 
1. 
1.916 
DuMez. 
Acetone. 
132.5 
2. 
Ether. 
122.9 
Table 122 —Iodine values of commercial preparations. 
Sample 
No. 
Date 
Observer 
Source 
Iodine value 
1. 
1916 
DuMez. 
Sharp & Dohme.. 
110.6 
128.3 1 
130.2 2 
2. 
Squibb & Sons.. 
3. 
“ 
Merck & Co. 
1 Labeled “Apiol-Fluid.” 
2 Labeled Apiol, Fluid, Green. 
Adulterations. 
A trace of copper was found to be present in the commercial 
samples examined. See under “Ash content.” 
OLEORESIN OF PEPPER 
Synonyms 
Aetherisches Pfefferextrakt, Nat. Disp. 1884. 
Ethereal Extract of Black Pepper, King’s Am. Disp. 1900. 
Extractum Piperis, Hirsh, Univ. P. 1902, No. 1244. 
Extractum Piperis Fluidum, U. S. P. 1850. 
Fluid Extract of Black Pepper, U. S. P. 1850. 
Oil of Black Pepper, King’s Am. Disp. 1900. 
Oleoresina Piperis, U. S. P. 1900. 
OlCoresine de Poivre voir, U. S. Disp. 1907. 
History. 
The oleoresin of pepper appears to have been first obtained 
as a by-product 1 in the preparation of piperine. Thus, Dr. 
Meli in France as early as 1825, reported having obtained the 
so-called “oil of black pepper” as a residue on separating the 
piperine from the alcoholic extract of the drug. The first 
notice of its use as a therapeutic agent apparently came from 
1 Jourdan, Univ. P. (1832), p. 346 
