1118 Wisconsin Academy of Sciences, Arts, and Letters. 
JJ. S. P. Text and Comments Thereon. 
The oleoresin of pepper has been official in the United States 
Pharmacopoeia since 1850, when it was recognized under the 
title of Extractum Piperis Fluidum. 
1850 
Extractum Piperis Fluidum 
Fluid Extract of Black Pepper 
Take of Black Pepper, 1 in powder, 2 heat, apint and a half of ether,® and 
a pound; expose the residue in a shallow ves- 
Ether, 3 a sufficient quantity. sel, until the whole of the ether has 
Put the powder into a percolator, 4 evaporated, 7 and the deposition of 
and pour ether gradually upon it until piperin in crystals, has ceased. Lastly, 
two pints of filtered liquor are ob- separate the piperin by expression 
tained. 5 From this distill off, by through a cloth, 8 and keep the liquid 
means of a water-bath, at a gentle portion. 
1860 
Oleoresina Piperis 
Oleoresin of Black Pepper 
Extractum Piperis Fluidum, Pharm., 1850 
Take of Black Pepper, 1 in fine pow¬ 
der, 2 twelve troy ounces; 
Ether, 3 a sufficient quantity. 
Put the Black Pepper into a cylin¬ 
drical percolator, 4 press it firmly, and 
gradually pour ether upon it until 
twenty-four fluidounces of filtered 
liquid have passed. 6 Becover from 
this, by distillation on a water-bath, 
eighteen fluidounces of ether,® and 
expose the residue, in a capsule, until 
the remaining ether has evaporated, 7 
and the deposition of piperin in cry¬ 
stals has ceased. Lastly, separate 
the oleoresin from the piperin by ex¬ 
pression through a muslin strainer, 8 
and keep it in a well-stopped bottle. 9 
