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PRINCIPLES OP BACTERIOLOGY 
Dengue 
Dengue is an acute infectious disease characterized by 
chills, fever, bone ache, etc.; the organism causing it is 
unknown. 
Rocky Mountain Spotted Fever 
Rocky Mountain spotted fever, a disease propagated by 
tick bites, is restricted to the region of the Rockies. The 
organism is unknown. 
Foot and Mouth Disease 
Foot and mouth disease occurs chiefly in cattle, sheep, 
and goats. It appears as a blistery eruption in the 
mouth and on the skin between the hoofs. The specific 
organism causing it is unknown. 
Hydrophobia, or Rabies 
Hydrophobia is a fatal infection of practically all 
mammalia. Although the organism is unknown, Pas¬ 
teur’s brilliant work has given us an absolute cure 
against it, if applied early. 
The infectious agent is transmitted in the saliva of 
the mad animal. By special staining methods (the best 
is that of Lentz) we can demonstrate in the brain of 
mad animals the so-called “Negri bodies,” which are 
characteristic of the disease. 
The Pasteur treatment consists of administering a vac¬ 
cine prepared from the cord of rabbits inoculated with 
the spinal infectious material. It absolutely prevents 
the disease if administered early. Whenever one is bit 
by an animal (usually a dog), the latter should be killed 
and its brain should be examined; the Pasteur treatment 
should be at once instituted. 
