74 
R. S. HUIDEKOPER. 
colloid or amyloid reaction. Inoculated fowls, or sound 
ones placed in contact with affected ones, showed the lesions 
in about five days; eleven days later the nodules reached 
the size of peas; by the third week the chickens became 
dejected, refused their food, and died with the appearance 
of a general cyanosis. Inoculations on sheep and goats gave 
negative results; on pigeons the tubercles appeared, but the birds 
recovered. 
From the small amount of literature on the subject, it is evi¬ 
dent that this disease in fowls is not analogous to variola, but to 
molluscum contagiosum. 
During the last summer Dr. Csokor received two living and 
three dead chickens, the last of a coop of thirty, which had died 
of the same trouble; the origin of the contagion was unknown. 
Dr. Csokor inoculated other fowls, and obtained the clinical symp¬ 
toms and pathological lesions of the so-called variola of fowls. 
He inoculated molluscum contagiosum from man in the combs 
of chickens, and obtained the same disease. From a review of 
the work, in this disease in man and in other animals, the author 
adopts the name given by Bollinger, of epithelioma contagiosum, 
as being the most proper. 
The clinical symptoms are dullness, with standing feathers, 
distinct chills of the whole body 5> smooth round, or mulberry 
shaped tumors, from the size of a hemp seed, to that of a bean, 
on the comb, gills, around the eyes, ears, and beak ; sometimes 
the top of the tumor was thrown up like a thick crust, with the 
tissue underneath very moist; the conjunctiva excessively red¬ 
dened, covered with an exudation of false membrane; the nos¬ 
trils filled with thick crusty masses; breathing short, accelerated 
and difficult; the birds stand with the beak on the ground ; heart 
beats rapid, and thumping, not to be counted; on the mucous 
membrane of the mouth and throat is found an analogous erup¬ 
tion, and false membranes. The course of the disease is short, 
the birds dying from asphyxia, due to the false membrane in the 
throat; in one case the lungs were hepatised. After the inocula¬ 
tion of three new birds, the symptoms showed themselves in 6 
days : by the 10th day the tumors were the size of peas; these 
