80 
PHYSIOLOGICAL PATHOLOGY. 
from Mr. Roux to perforin the operation, and now performs it 
whenever we require it, almost without accident. It occupies so 
little time that the last monkey operated upon was chloroformed, 
trephined, and had recovered from the effects of the anesthetic in 
twenty minutes, and in less thau fifteen minutes more he was 
eating a fig. 
To be brief, I will give you a concise summary of our attained 
results: 
1. In a previous communication I announced that the most 
frequent result of the inoculation of the rabid virus into the 
circulating system is paralytic rabies, with absence of rage and 
rabid barking. It was therefore to be supposed, that under these 
conditions, the rabid virus ought first to fix itself and grow upon 
the marrow. In destroying dogs at the moment of the appearance 
of the first symptoms of paralysis, and also afterwards studying, 
comparatively, the virulent power of the marrow, principally at 
the lumbar bulbe and the virulency of the bulb, we have found 
that the marrow could be rabid where the bulb was not. 
2. We have previously shown, that in cases of rabies, the 
virus had its seat both in the encephalon and in the mar¬ 
row. We have more recently, looked for it in the nerves proper 
and in the salivary glands. We have succeeded in giving rabies 
with portions of the pneumogastric nerve, whether taken at its 
origin, at its exit from the cranium, or at points more distant. 
The sciatic nerves have also shown us the virus, as well as the 
maxillary, parotid and sublingual glands. The entire nervous sys¬ 
tem, from its center to its periphery, is then susceptible to the 
cultivation of the rabid virus. We may now understand the 
nervous superexcitation manifested in many cases of rabies and 
so often evident in man through the peculiar symptom of 
aerophobia. 
The virulency of the sailva aud of the salivary glands has 
been observed in dogs rendered rabid by intra cranial or intra¬ 
venous inoculation, as upon dogs affected with so-called spontane¬ 
ous rabies. 
3. We have before observed that the rabid virus can be pre¬ 
served, with all its virulency, in the encephalon and in the mar- 
