170 
G. SEE. 
cat, no more phthisic than the dog, has been successfully treated 
by Chauveau and Toussaint. And lastly, if, like Krishaber and 
Dieulafoy, one chooses the animal whose constitution, physiolog¬ 
ical and morbid, resembles most that of man, which is the 
monkey, it is easily rendered tuberculous, even in the most per¬ 
fect condition of health. 
DEVELOPMENT OF THE INOCULATED TUBERCULOSIS. 
1st. Tubercxdizing effects of inoculations. —Inoculation is prac¬ 
ticed in the subcutaneous cellular tissue, in the peritoneum, or in 
the anterior chamber of the eye. This last method is the neatest 
and the surest. The inoculation is performed with a fine lan¬ 
cet charged with an almost microscopic tuberculous fragment, or 
with a Pravaz syringe filled with a dilution of tuberculous matter, 
or of sputa. Here is what one observed, especially when done in 
the peritoneum, where the infection takes place most rapidly : 
Local Tuberculosis. — A few days after inoculation a 
local trouble takes place, which does not interfere with general 
health. 
Ge7ieralized Tuberculosis. —Then, after a varying length of 
time, the animal becomes weak, becomes marasmic, and dies after 
a colliquative diarrhoea, as all phthisics do. At the post-mortem— 
one observes—besides the local tubercle, already caseous in its 
nature, small miliary granulations appeared all round the inocu¬ 
lated points. The tuberculous swelling of the glands, and more 
or less easeiform granulations in the lungs, the intestines, the 
liver, the spleen, the kidneys and the peritoneum ; this is general 
tuberculosis. 
Inoculability of Artificial Tubercles. —Tuberculosis thus pro¬ 
duced is the true, the bacillar kind, as it can easily be inoculated 
to animals both of the same or of different species, and with cer 
tainty during several generations or successive series. 
II. — Counter-proofs and Objections. —The true character of 
this experiment has been denied by some ; formal objection has 
been made, stating that these were merely simple inflammatory 
nodules, whose appearance simulated tubercles, but whose mode 
of production was not specific. 
