INFLAMMATION. 
Ill 
cement substance. Thus we have formed minute openings, 
called stigmata, which are gradually enlarged into stomata. 
Winniwarter found, when such vessels were injected, that an es¬ 
cape of the injected substance may take place through these 
openings.” 
If this condition exists during inflammatory action, it is very 
probable that diapedesis of colored and migration of colorless 
corpuscles may take place through these abnormal openings, the 
result of over-distension of the capillary blood-vessels. 
Furthermore, Purves has found that the capillary vessels, 
through which colorless corpuscles have migrated, upon being 
stained with nitrate of silver, show that the migration is limited 
to the intercellular cement substance of the endothelial wall. 
Before taking up the third important change in inflamma¬ 
tion, namely, alteration in the nutrition of the inflamed parts, I 
will briefly summarize the various processes I have considered in 
the foregoing. 
It has been shown that in inflammation the arteries are first 
dilated, that this dilatatio 1 slowly increases for several hours, that 
the length of these vessels is increased so that they become tor¬ 
tuous, that the blood current is increased, that this acceleration in 
the flow of blood seldom lasts longer than an hour, that the veloc¬ 
ity of the current then begins to diminish and may continue until 
complete stasis in the capillaries is the result, that the latter con¬ 
dition is attended with exudation of liquor sanguinis and migra¬ 
tion Tif blood corpuscles. These former constituents of the blood 
are termed “ products of inflammation,” and collectively consti¬ 
tute what has commonly been called coagulable lymph. 
Perhaps it will be well to state, in connection with the exuda¬ 
tion of liquor sanguinis, that the constituents of this fluid resem¬ 
ble the plasma of the blood, except that it contains less albumen. 
“ It contains,” says Flint, “ the fibrine generators, and in most 
places finds the conditions necessary for the spontaneous coagula¬ 
tion of the fibrin. A fibrinous effusion is in the vast majority of 
cases an inflammatory exudation. In simple inflammation of 
mucous membranes and in suppurative inflammation (abscess), no 
fibrin is formed.” (Tg u continwd ) 
