EXPERIMENTAL PATHOLOGY. 
317 
1st. All operations on blood vessels ought to be accompanied 
by every known antiseptic precaution. 
2d. The catgut antiseptic ligature is the safest of all the 
means in use for the occlusion of blood vessels. 
3d. The clot which is formed after the application of the 
ligature has no active agency in the obliteration of the blood 
vessel. 
4th. The cicatrization is due to the proliferation of the con¬ 
nective tissue and of the endothelium. 
5th. The period of permanent obliteration for arteries is 
from the fourth to the seventh day, and for veins, from the third 
to the fourth. 
6th. Double aseptic ligation is preferable to single for large 
arteries, when applied near to collateral divisions, and must always 
be employed in a case of varicose veins. 
GANGRENOUS SEPTICAEMIA. 
By Mb. Chatjveau. 
The author, in answering objections made to a former com¬ 
munication, says that in his view the agent of gangrenous septi¬ 
caemia is no other than the septic vibrio of Pasteur. This is the 
most 'perfect of the anerobic microbes, and from this results the 
necessity of cultivating it apart from the atmospheric air. It is 
an error to accuse Mr. C. of overlooking or ignoring the nature 
of the liquids which serve as vehicles. For if one takes from a 
donkey or a sheep which has died from an intra-vascular injection 
of gangrenous septicaemia virus, a drop of pericardial or pleural 
serosity, aud with this inoculates a guinea pig, this animal will 
die of gangrenous septicaemia. But if the same serosity has first 
been filtered and deprived of its corpuscular parts, with its cellular 
and morbid elements the inoculation does not prove fatal. 
It is from the portal vein of an animal dead for some time that 
the blood containing the septic vibrio must be taken. The lesions 
produced by this blood are the same with those which follow the 
subcutaneous inoculation of infectious serosities taken from a man 
who has died from rapid gangrene. And again, there is no dif- 
