M. L. PASTEUR. 
70 
they are on this account, even, destined to modify our ideas very 
materially as to the general principles underlying the contagia 
and the contagious fevers. At present I can do no more than re¬ 
fer to this aspect of the question, leaving the practical applica¬ 
tions to suggest themselves, as I believe they will, to every one 
who ponders over the many mysteries connected with the phenom¬ 
ena of this class of diseases. 
{To be continued .) 
PATHOLOGICAL PHYSIOLOGY. 
A STATISTIC OF THE PREVENTIVE VACCINATION AGAINST 
ANTHRAX. 
By M. L. Pasteur. 
According to Mr. Boutet, reporting the result of the vaccina¬ 
tions performed in the Department of Eure-et-Loir,.the number of 
sheep vaccinated amounts to 79,392. The average annual death 
rate of these flocks for the last ten years was 7,237, or 9.01 per 
100. Since the vaccination only 518 animals have died ; an aver¬ 
age of 0.65 per cent. It must be remarked that this year, prob¬ 
ably on account of the great dampness, the mortality in this de¬ 
partment has been only of 3 per 00.10. The losses there ought 
to have been 2,382 insted of 518 after the vaccinations. 
In the flocks which were only partly vaccinated, 2,308 were 
and 1,659 were not operated upon. The deaths in the first 
amounted to 8, or 0.4 per 100, and upon the second 60, or 3.9 
per 100. In this department all animals were submitted to the 
same conditions of soil, lodging, food and temperature, and con¬ 
sequently were submitted to exactly identical influences. 
Among cattle, 4,562 animals were vaccinated. In this num¬ 
ber the average yearly deaths were 322. Since the vaccinations 
only 11 cows have died ; the annual mortality, which was 7.02 
per hundred, has been 0.24 per 100. 
On account of swellings, generally without gravity, taking 
place in horses, and as the mortality from anthrax in this species 
is quite low, the vaccinations has not been carried on a large 
scale. Only 524 horses were vaccinated, amongst which three 
died between the two inoculations 
