PATHOLOGICAL PHYSIOLOGY. 
521 
made three weeks after the second vaccination, and renewed six 
days after, with very virulent blood, and repeated a third time 
always with anthrax blood, very rich in batonnets. The success 
was complete. Notwithstanding the accumulation of extremely 
strong virus, the nine living animals recovered perfectly. They 
possessed a perfect immunity. 
These extremely favorable results of this experiment prove 
that the method of the rapid heatings can be applied with success 
to the practice of preventive inocculation, and deserves to be 
studied in this point of view. 
If we wish to appreciate the practical value of a mode of pre¬ 
ventive inoculation, we must look at it from the three fold point 
of view, of facility of execution, inocuity of the operation, and 
the certainty of the results (the immunity) looked for. 
In respect to the first consideration, it is certain that the 
method is of easy practice for all. 
In relation to the inocuity, the facts reported, with many 
others not referred to, show that this method is surpassed by 
no other. 
Upon the question of immunity, it can advantageously com¬ 
pare with anjf other process. This marked immunity, observed 
experimentally under various circumstances, may be referred to 
the great activity of the second liquid, called vaccinal, not heated, 
which greatly resembles the strong virus, and must produce a 
powerful impression upon the animal economy .—Academie des 
Sciences. 
DETERMINATION OF THE CAUSES WHICH DIMINISH THE RECEP¬ 
TIVITY OF SOME REGIONS OF THE ORGANISMS, FOR THE 
VIRUS OF SYMPTOMATIC ANTHRAX AND TRANSFORM A 
FATAL INTO A PREVENTIVE INOCULATION. 
By M. M. Arloing, Cornevin and Thomas. 
In inoculating cattle and sheep with the virus of symptomatic 
anthrax, the authors have observed, as Dr. Williams had done 
for the virus of contagious pleuro-pneumonia in cattle, that the 
microbes, inserted in the subcutaneous cellular tissue of the tail, 
did not give rise to the disorders which they produce in other re¬ 
gions of the body, and the superior part of the extremities. This 
