PATHOLOGICAL PHYSIOLOGY 
557 
bronchi. Such, again, as those which Professor Laulanie, of 
Toulouse, has found present in the eggs or larvae of a nematoid 
strongylus, the strongylus vasorwn ; a most interesting fact in 
the general history of tuberculisation, and the truth of which 
has been confirmed by Mr. Cornil of the Society of Biology. 
If I am not in error, Professor Willemin, in the beginning of 
his experiments upon the contagiousness of tuberculosis, ob¬ 
served in the rabbit a pseudo tuberculosis of a parasitic (acariau) 
nature ; the nuclei of the tubercles being formed by the acari. 
It were useless to multiply facts of this description. We have 
the proof that certain pulmonary nodosities of tuberculous ap¬ 
pearance have for their nuclei certain well-known living corpus¬ 
cles, which are manifestly their originating cause, and from these 
facts the conclusion is unavoidable. The rapid development of 
the nodules which fill the lungs whenever the microbe in question 
is (by whatsoever means) introduced into the organism, and 
which is susceptible of indefinite cultivation, justifies the state¬ 
ment that it is this which constitutes the true virus of glanders. 
These microbes, carried by the circulation into the pulmonary 
parenchyma, form by their growth the active nuclei around 
which the irritated and inflamed tissue discharges the products of 
its proliferation and of its pathological secretions, and this mass 
constitutes the glanderous nodosity. Is not this theory con¬ 
firmed by the constant presence of the specific microbe in the 
network of the nodosity ? 
The same explanation may account for the phenomena of the 
ulceration of the respiratory mucous membrane, which consti¬ 
tutes one of the predominant characters of glanders or farcy. 
Let us, for instance, consider it in an acute case, where these 
phenomena are most distinctly marked. 
The external manifestations following the inoculation of 
glanders are, by choice , more marked in the pituitary mucous 
membrane and the skin. Upon the pituitary membrane they 
consist in a pustular eruption, rapidly replaced by ulcerations, 
which themselves, rapidly growing in size and in depth, soon 
change it into a single large wound, resting on a network whose 
elements soon break off and change into a sort of putrid secretion. 
