LEUCOC YTHEMIA. 
167 
In a narrow test tube, kept at a low temperature, the slowness 
of the coagulation causes it to divide into two parts—the superior 
of a milky-greyish white, opaline (that which resembles the opal; 
fluid milky, said to he opaline); the inferior, deep red. This 
separation of the blood in two clots is very characteristic in all 
animals in which the clot is monochromous. 
In the leucoeythetnic horse, coagulation gives three distinct 
layers ; an inferior deep red, formed of red globules; a superior 
slightly yellow, semi-transparent, formed of fibrine ; a middle, 
more or less thick, formed of a dirty-white opaque, constituted of 
leucocytes and globulins. 
General disease diasthetic, characterized by the more or less 
rapid production in all the organs of neoplasms, of which the in¬ 
timate structure is like that of the lymphatic ganglia. These 
neoplasms may present themselves under form of more or less 
voluminous masses, or as a diffuse infiltration in the thickness of 
organs. 
In the first case their aspect to the naked eye is still that of 
the lymphatic ganglions; they are more or less irregularly 
rounded, of slight consistence; their section is smooth, of a grey 
ish or whitish color. On scraping, they give an opaline, milky 
fluid, which is shown by the microscope to be composed of a con¬ 
siderable quantity of lymphatic globules, hlo breaking down. 
Signs and Diagnosis. —Leucocythemia is only a contingent fact 
—an accessory to—only a symptom—not constant; the essential 
part consists in enlargement of the lymphatic glands. 
What first draws attention to the disease is loss of strength 
and the animal soon getting out of breath at work ; the appetite 
becomes capricious ; desire for liquids ; emaciation. The mucous 
membranes have a porcelain-white color, as if all the blood had 
been driven out of the vessels. The patient becomes weaker and 
weaker; can hardly walk ; knuckling over on hind legs ; front legs 
separated ; head and neck extended ; stops from dyspnoea after a 
few steps ; intense emaciation, or may refuse to move. Then 
comes constant oppression, roaring at rest, tympanites, diarrhoea 
foetid, oedema, hemorrhages and death in the most complete 
marasmus. 
