EXPERIMENTAL PATHOLOGY. 
231 
severe epidemics this period is marked by the greatest number of 
severe complications and fatal terminations. 
3d period, fifth and sixth weeks. 
PHENOMENA OF REGRESSION. 
We may assume regression as beginning when the encapsula¬ 
tion of the parasites commences to take place, which comes to 
pass about the twenty-eighth day of the invasion. The duration 
of the disease in severe cases cannot be well fixed, as it may ex¬ 
tend over many months before all disturbances have come to an 
end. In most cases the recovery begins during the regressive 
period and goes hand in hand with the regeneration of the mus¬ 
culature of the organisms. Most persons are able to assume 
their vocations after the sixth week. The urine, which lias been 
thick, cloudy and lessened in secretion, begins to become too 
clear and more profuse in quantity with the twenty-eighth day. 
On account of the preeminence which the pains in the muscles 
assume over the other symptoms during this period, it may well 
be called the rheumatoid. 
(To be continued .) 
EXPERIMENTAL PATHOLOGY, 
UPON THE DURATION OF THE EFFECT OF THE PREVENTIVE IN¬ 
OCULATION IN SYMTOMATIC ANTHRAX AND UPON THE TRANS¬ 
MISSION OF IMMUNITY FROM THE MOTHER TO ITS PRODUCT 
IN THE BOVINE SPECIES. 
By M. Arloing, Cornevin and Thomas. 
A. It is important to know the duration of the immunity en¬ 
joyed by animals of the bovine species against symptomatic an¬ 
thrax by the intra venous injection of the virus. It has been 
already reported that thirteen animals vaccinated in February, 
1881, were, in October, eight months after, still enjoying immu¬ 
nity. Recent experiments have shown that this will last for 17 
months. A heifer had been inoculated on the 30th November, 
1880. On the 21st of April, 1882, one cubic centimeter of vir¬ 
ulent pus was placed in her crural muscles. A cobaye inocu¬ 
lated with the same matter died in 24 hours. 
