AN INQUIRY. 
279 
(sarcocle, mallosa, verichon), and kidneys , specific papules of the 
choroid coat of the eye, and, furthermore, inflammation of the 
parotid gland. 
In the nose the cartilages become exposed and necrosed, the 
septum, vomer and palate bones are disorganized. In the phar¬ 
ynx, larynx and trachea are frequently found papules and ulcera¬ 
tions. The growths and ulcerations in the larynx may lead to 
oedema of the glottes. The cartilages and bones are often in¬ 
volved secondarily in the destructive action of the adjacent spe¬ 
cific affections, the ulcers and abscesses. In rarer instances the 
bones and periosteum are the primary seat of the specific growths 
and inflammatory process. In cases running a chronic course, 
with moderate ulceration of the nose and larynx, glanders may 
acquire a very strong resemblance to certain forms of syphilis. 
“ The contiguous parts become involved in the diseased pro¬ 
cess ; for instance, if the disease is situated upon the head, the 
bones of the skull and face and more particularly the frontal 
bone are all affected, becoming necrosed; while even upon the 
inner surface of the skull, between the bone and the dura mater , 
purulent collections may be formed ( y achy meningitis externa). 
In other cases tubercles may appear in the periosteum of the 
skull, in the dura mater , and even in th o, plexus charoides. In 
the human subject , just as in the horse, the nasal affection often 
fails to appear until the latter stage of the illness , which affords 
convincing evidence that in both species these symptoms cannot 
be regarded otherwise than pathognomonic. 
Of the remaining tissues of the body, the muscles form un¬ 
questionably the most frequent seat of specific changes. According 
to Kiittner, the specific nodules are mostly situated in the biceps, 
the flexors of the forearm , the rectus and the pectoratis, and 
finally at the point of insertion of the deltord.” (Ziemssen’s Cy 
clopsedia, Yol. Ill, article Glanders.) 
By way of comparison again, in later stages of these diseases, 
let us observe first what effect syphilis has on the muscular tis¬ 
sues, and, second, what affinities they have in a general way in 
common. 
“ The syphilitic disease may locate itself in the most various 
