PATHOLOGICAL PHYSIOLOG Y. 
351 
These animals, placed in several locations, were kept under 
observation. I could easily observe the development and ordi¬ 
nary progress of the disease in local tubercles and hard swell¬ 
ings of the parotid ganglion. 
The general infection showed itself very rapidly in all these 
animals. It is a curious fact that the rabbits, which received th e 
heated fluid, died first. 
One of the pigs was killed two months after the injection. 
The post mortem showed a local caseous tuberculosis, and an 
enormous parotid ganglion with cretaceous spots. The lung 
showed great quantities of grey granulations, and there were 
tubercles in the spleen and liver. 
After three months, another pig was killed, as was also the 
one used as proof which had used the fluid unheated. The dif¬ 
ference between the lesions of the two was very slight, though 
they were more advanced in the last. 
The pulmonary tubercles of the pigs which had received the 
heated fluid were then inoculated to rabbits. They became dis¬ 
eased, and two of them, killed three months after, showed numer¬ 
ous lesions in the lung, spleen, kidneys and serous membranes. 
Two of the pigs inoculated with the heated fluid are yet alive, 
after five months; one, however, is nearly dead. 
Of the four rabbits inoculated with heated fluid, one died 
accidentally after thirty-five days. In this case the parotid gang¬ 
lion was caseous, but the general infection did not yet exist. 
The other rabbits died with general tuberculosis, from the 164th 
to the 170th day ; one presented lesions of the bones, largely de¬ 
veloped on the anterior legs; the articulations of the shoulder 
and arm contained caseous pus, the articular surfaces and even a 
part of the diaphysis being entirely destroyed. 
As to the rabbits inoculated with the cold fluid, one was killed 
after forty-three days, and exhibited numerous gray tubercles in 
the lungs and liver. The second, a doe, is yet iiving. Since the 
inoculation she has had three litters, in the first of which the 
little one died the day after birth. In the second she had five, 
which are kept with those of the third, in order to study the effect 
of heredity. As the doe is now in an advanced state of tuber- 
