CHICKEN CHOLERA. 
135 
liens have died, and a post mortem inspection shows that, without 
doubt, the disease had infected the organism, either by the anterior 
digestive organs, or, and oftener, by the intestines, which are 
generally much inflamed, and sometimes extensively ulcerated, 
resembling in their lesions those of typhoid fever.* The five 
other hens, not vaccinated, are diseased; one in the most serious 
condition.! Of the twelve vaccinated, none died, and all are yet 
alive and in good health. 
We may then present a resum6 of the results as follows: 
It is the presence of the parasite in the body which produces 
the disease commonly called chicken cholera , and caused the death 
of the fowl. 
From the time when the culture ceases to be possible in the 
fowl, the disease cannot appear. Hens are then in the constitu¬ 
tional condition of animals which are never affected with the 
chicken cholera. The condition is the same as if they had been 
vaccinated from birth, the foetal development, which formed the 
food proper of the microbes, having never been introduced in 
their bodies, or because these nutritive elements have disappeared 
in youth. 
There is certainly no ground for surprise at discovering con¬ 
stitutions sometimes ready, sometime rebellious to inoculations ; 
that is, to the culture of certain kinds of virus, when, as I have 
shown in my first note, one may see that the bouillon of yeast, 
prepared exactly like that of muscles of chickens, remains entirely 
unfit for the culture of the parasite of the chicken cholera, while 
it is perfectly good for the culture of a number of other micro¬ 
scopic species, especially the bacteridse of anthrax. 
The explanation resulting from the facts, as well as of the 
constitutional resistance of certain animals, (as that of the immu¬ 
nity created in hens by prophylactic inoculations), has in it 
*Tbe blood is full of microbe, aud tbe iuterual organs are quite often 
covered with pus and false membranes, principally by the intestines, through 
which the microbe seems to have made its entrance. 
fit died the 8th of April; another the 23d; three recovered. Altogether, 
nine died out of twelve. The 8th and 23d of April, the blood of the dead was 
found to be loaded with the microbe, and the abdomen showed lesious of 
peritonitis with false membranes. 
