HUMAN AND ANIMAL VARIOLAS. 
195 
instance of accidental infection was reported—a farmer’s wife who 
had milked a cow in which the pustules had arrived at maturity, 
had a vaccine vesicle on the thumb. In 1874, twenty-four cows 
and four heifers were reported, but complaints are made that the 
information with regard to these came too late to make many of 
them available for vaccination—the pocks being either in the last 
stage, or ruptured, and only sores remaining. Nevertheless, 
lymph was procured from twelve, and with this twenty-five to 
thirty children were successfully vaccinated. Some interesting 
details are given with regard to these cases of cow-pox, one of 
which was an example of variola succineoe. Surgeon Loftier, of 
Rottenburg, received on April 20th, one of the heifers—a two- 
year-old animal, twenty-five to thirty weeks pregnant, and very 
healthy. On the two posterior teats of the right side were three 
fine pustules, and on the last teat of the left side was another. 
On opening these a yellowish glutinous fluid escaped. On the 
23d, new pustules appeared. The udder and teat were hot, and on 
the latter were several small and large oval pustules, each with a red 
areola. When opened there flowed a yellow thick lymph from 
them ; there was a very small quantity of clear lymph at the end. 
Two children were inoculated by puncture, and an additional 
quantity of lymph mixed with tepid water, was poured into the 
wounds. In one child there were developed four perfect and 
fine ( Vollkommen schone) silver-hued pustules, and in the other 
child one pustule. From these two children five others were suc¬ 
cessfully vaccinated. Another similar case is related by Dr. Kie- 
ser, of Gmund, in which the cow was three years and a half old, 
and yielded lymph with which three children were vaccinated, and 
from these a large number. The details of these eases are full 
of interest, but I cannot dwell upon them here. I may mention, 
however, that among the cow T s were two cases nf V. vacc. nigr. 
In 1875, twenty-three cases of genuine, and seventeen of spurious 
cow-pox were reported. Nine of the former yielded satisfactory 
inoculations in children, and the owners of the animals were con¬ 
sequently rewarded. One cow was reported to have shown a suc¬ 
cession of genuine pox for two years; it was seven years old, and 
was pregnant with the fifth calf. On the udder, on April 14th 
