260 
N. COLIN. 
inoculation will produce exactly the malignant pustule, nor the 
malignant oedema of man, while, secondly, witli others, similar 
accidents may be developed in various degrees and under well 
characterized forms. I therefore believe I am serving the cause 
of pathology in presenting the results I have readied, relating to 
the local accidents of anthrax. 
I begin by those referring to the symtomatology: 
I. 
When in a puncture or scarified spot, or any wound of the 
skin of an animal but slightly susceptible to attacks of anthrax, 
one inserts a little carbuncular blood, and in such a way as to 
reproduce the condition under which in man the malignant pus¬ 
tule seems to develop itself, the results observed greatly vary. 
For example : 
1st. A simple canal, semi-closed, which for several days pre¬ 
serves the inserted vesicular matter. 
2d. A diffused erythema, of short duration, and disappearing 
almost immediately upon its inception. 
3d. A simple malignant pustule, more or less prominent, red 
and umbilicated, oozing, first a serous, and then a sero-purulent 
fluid. 
4th. A simple oedema, without change in the condition of the 
skin. / 
5th. A pustule followed by oedema. 
6th. An oedema followed by pustule. 
7th. A pustule and oedema appearing simultaneously. 
8th. A pustule with oedema and erythema. 
9th. A phlegmonous tumor. 
10th. Finally, a simple bubo, with surrounding lymphangitis. 
These ten forms of local accidents of anthrax are not equally 
frequent. They cannot be all observed, except upon the dog, who 
contracts the disease with difficulty. And again they can be 
noted on him only by varying the regions in which the virulent 
liquids are inserted. For example, it is at the internal face of the 
ear and the axilla that the erythema shows itself; it is at the 
sheath round the mammse, near the testicular envelope, and at 
