264 
M. H. TOUSSAINT. 
there a small one, conical, closed, with narrow areola; a little 
further, a flat pustule, pale, without peripherical oedema; by its 
side, another which aborts, or even a simple dry scratch without 
apparent reaction. Variations quite numerous in the different 
steps of the morbid changes are also observed. Now, the pustule 
which oozes serosity is one dry or another suppurating. Opposite 
that, where the resolution is going on well, are seen others which 
become purplish, sloughing round their summit, or which ulcerate 
superficially, or at the base of which large sloughs are taking 
place. We may afterwards notice that those pustules differ also 
in respect to the virulency of the liquid which they secrete or by 
which their tissue is impregnated. 
The fact of the existence of numerous varieties of carbuucu- 
lous pustules in animals, explains sufficiently to us the lack of 
agreement in the descriptions given of the malignant pustule of 
man. Each observer has described only the types he has himself 
seen; and moreover he has described of these only their character 
in a somewhat advanced period, having rarely followed their de¬ 
velopment from the beginning. What seems dissimilar in the 
symptomatology of the accident must explain realities and not 
errors of observation. In the future, instead of looking for an 
almost uniform characteiistic condition, which would be wholly a 
fictitious idea, we shall be required to distinguish and to define 
all the types of the carbuncular pustules, as well as to determine 
what they possess in common. 
(To be continued .) 
IMMUNITY AGAINST ANTHRAX OBTAINED BY PRE¬ 
VENTATIVE INOCULATIONS. 
By M. H. Toussaint. 
The numerous experiments made by me during past years, 
upon the anthrax, have proved that the bacteridie, when intro¬ 
duced into the economy of animals liable to take the disease, are 
not there in absolutely normal conditions, though their develop- 
