HUMAN AND ANIMAL VARIOLAS. 
321 
It is very important to note that two experiments were made 
to test the transmissibility of human syphilis to calves. At the 
seat of inoculation there was formation of pustules, induration of 
the udder and the lymphatic glands, which continued for about 
a month ; but otherwise the animals remained in good health. 
The conclusions arrived at by the Commission were as follows : 
1. The results of inoculation by puncture and incision are the 
same, though in the thicker skin of adult man or bovines incision 
is preferable; for children puncture is not so painful, and takes 
less time. Incision alarms the mother, as it causes a little 
bleeding. 
2. The time of year has no marked influence on the success 
of vaccination or re-vaccination, though temperature will hasten 
or retard the appearance of the eruption. 
3. The form of pustulation is in man and animals essentially 
the same, except that in cattle there is less lymph, and the um- 
bilicated appearance of the pustule is not so distinct. 
4. The lymph from different sources has not the same potency. 
In horse-pox, 72.9 per cent, of the inoculations were successful; 
in natural cow-pox, 72.8 ; and in artificial cow-pox, 41.19. 
5. Humanized lymph has double the potency of that from 
animals. 
6. Humanized lymph conveyed to cattle diminishes in activity. 
7. Natural cow-pox lymph inoculated on mankind increases in 
potency. 
8. Comparison of the primary lymph with that of re-vaccina¬ 
tion is greatly in favor of the former. 
9. Human smallpox cannot be transmitted to cattle. 
10. The syphilis virus can be implanted in bovines, and suc¬ 
cessfully re-transferred to man. 
11. Humanized lymph possesses more tenacity of activity than 
any other; with properly preserved crusts or dry lymph, animals 
can be inoculated successfully. 
12. Lymph is more easily procured from man than from ani¬ 
mals. 
13. The microscope gives no indication of the activity of 
lymph. 
