NEW RESEARCHES UPON PLEURO-PNEUMONIA, ETC. 421 
reacts tlms upon the whole organism. These infiltrations of plastic 
matter in the places where inoculation has been made and where 
there is abundance of connective tissue, often take so rapidly and 
abundantly, on the dew-lap for instance, that the animal succumbs 
soon to them. 
That is what was observed in the unfortunate inoculations, 
imprudently made by M. Cloes, at the castle of Herkenrode, near 
Hasselt, where almost all the animals inoculated on the dew-lap 
died. The lesions of the muscles are identical to those of the 
lungs ; here again it is the interfascicular connective tissue which 
is the seat of the infiltration. 
When one incises these swellings, the quantity of liquid 
which escapes may be valued at several liters a day. These swell¬ 
ings generally assume extraordinary size, cover large surfaces of 
tissues and look like hepatized lungs, in which some tissues weigh 
as much as 20 or 30 kilogrammes. 
Exudative pleuro-pneumonia ends ordinarily, whatever is done, 
in the death of the animal by asphyxia; the lung, most often the 
right, and sometimes both, is so much filled with the characteristic 
exudation that it becomes impermeable. If the patient does not 
die with asphyxia, the lung being only partly hepatized, the dis¬ 
ease hangs on and most of the organs, especially the liver, be¬ 
come infiltrated, the intestines present inflammatory patches, exu¬ 
dations of serosity take place in the splanchnic cavities in the cel¬ 
lular tissue, the muscles become soft, etc., and the animal succumbs 
after several days of the disease. 
Sometimes animals suffer only slightly from the effects of con¬ 
tagion, and recover rapidly; but at other times, in exceptional 
cases, the disease ends by the encysting of a part of the lung, 
which forms a sequestrum, ordinarily very hard, in the middle of 
the parts of the lung still healthy, and the animal may thus live 
quite a long time in an apparent state of health. These very 
curious lesions are found only when the animal is destroyed for 
consumption. 
This phenomena is altogether like that observed by M. Past¬ 
eur in chicken cholera. He says : “ In the cases of recovery, the 
parasite is stopped little by little in its development, and disap- 
