422 
M. COLIN. 
pears at the same time that the muscle hardens and lodges itself 
in a cavity whose whole surface resembles that of a granulating 
wound of healthy nature. The necrosed part finishes by forming 
a sequestrum, so well isolated from the cavity where it is con¬ 
tained that one feels it under the finger, through the skin, in the 
interior of the muscle, and by the smallest incision can take hold 
of it with the fingers and extract it. 
(To be continued .) 
EXPERIMENTAL ANALYSIS 
OF THE MALIGNANT PUSTULE AND CARBUNCU- 
LOUS (EDEMA; DETERMINATION OF THEIR 
VARIOUS FORMS AND OF THEIR 
DEGREES OF VIRULENCY. 
By M. Colin, of Alfort. 
Continued from page 366. 
Therefore, though everything has seemed identical at first 
in our two animals, the carbuncular process has changed charac¬ 
ter at a given time. In remaining localized in one, it has allowed 
the virulency to die out in situ. In spreading in the other, it has 
extended to the whole of the organism. In the first case, the 
lymphatic system has remained healthy; in the second, it became 
affected, and as a mean of connection between the starting point 
and the rest of the economy. 
If we wish to have the material proof of the intervention 
of the lymphatic glands in the morbid process by which anthrax 
is generalized and become fatal, let us take again two dogs, 1 
mean two adult sluts: Let us insert on one the virulent liquid in 
the mammae, in front of the pubis, near the ganglions, and on the 
other, on the contrary, in the anterior mammae between the um¬ 
bilicus and the abdominal appendage of the sternum, consequently 
quite far from the inguinal and axillary ganglions. On this one, 
